References: 1. Taneja PA, Snyder HL, de Feo E, et al. Noninvasive prenatal testing in the general obstetric population: clinical performance and counseling considerations in over 85 000 cases. Prenat Diagn.
2016: 36:1-7. 2. Bianchi DW, Platt LD, Goldberg JD, et al. Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencing.Obstet Gynecol. 2012 May;119(5):890-9. 3. Bianchi DW, Parker RL,
Wentworth J, et al. DNA sequencing versus standard prenatal aneuploidy screening. N Engl J Med. 2014 Feb 27;370(9):799-808. 4. Taylor-Phillips S, Freeman K, Geppert J, et al. Accuracy of non-invasive prenatal
testing using cell-free DNA for detection of Down, Edwards and Patau syndromes: a systematic review and meta-analysis. BMJ Open. 2016 Jan 18;6(1):e010002. 5. Verinata Health, Inc. Analytical validation of
the verifi ®prenatal test: enhanced test performance for detecting trisomies 21, 18 and 13 and the option for classification of sex chromosome status. http://www.prenatalsafe.it/pdf/bibliografia/10_verifi_white_
paper_Letter-Size_11-16-2012.pdf. Published 2012. Accessed March 17, 2016. 6. Practice Bulletin No. 163: Screening for fetal aneuploidy. Obstet Gynecol. 2016 Mar 3. 7. Benn P, Borrell A, Chiu RW, et al. Position
statement from the Chromosome Abnormality Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis. Prenat Diagn. 2015;35(8):725–34. 8. Anthem. Cell-free fetal DNA-
based prenatal screening for fetal aneuploidy. https://www.anthem.com/medicalpolicies/policies/mp_pw_c150729.htm. Revised: September 2015. Accessed March 17, 2016. 9. Gregg AR, Gross SJ, Best RG, et al.
ACMG statement on noninvasive prenatal screening for fetal aneuploidy. Genet Med. 2013;15:395–398. 10. Committee Opinion No. 640. Cell-free DNA screening for fetal aneuploidy. Obstet Gynecol. 2015;126
(3):e31–e7. 11. Devers PL, Cronister A, Ormond KE, Facio F, Brasington CK, Flodman P. Noninvasive prenatal testing/noninvasive prenatal diagnosis: the position of the National Society of Genetic Counselors.
J Genet Couns. 2013;22:291–295. 12. Neufeld-Kaiser WA, Cheng EY, Liu YJ. Positive predictive value of non-invasive prenatal screening for fetal chromosome disorders using cell-free DNA in maternal serum:
independent clinical experience of a tertiary referral center. BMC Med. 2015 Jun 2;13:129.
NON-INVASIVE PRENATAL TESTING